INTELLIGENT BREAST CANCER IDENTIFICATION SYSTEM USING DEEP TRANSFER LEARNERS WITH SVM CLASSIFIER MODELS

Main Article Content

Dr. Panduranga Vital Terlapu1,Dr.Naresh Tangudu2*, K Kavitha3, Dr. Ramesh Yegireddi4, V Ashok Gajapathi Raju5, G V L Narayana6

Keywords

Breast Cancer, Deep Learning, Feature Extraction, Inception-v3, SVM, Transfer Learning

Abstract

Breast cancer (BC) is the most common disease in the medical field. It is the second leading cause of cancer-related deaths after lung cancer, especially in women. Early detection and treatment of the disease are essential for the survival of patients. Ultrasound image analysis is one of the procedures for breast cancer identification. We collected ultrasound cancer image data from the Kagle Data Repository. Nowadays, automated intelligent cancer detection through image datasets using deep learning methods is one of the most efficient techniques. This research analyses and extracts the features of breast ultrasound cancer images using deep transfer learning neural networks such as Inception V3, VGG-16, and VGG-19 networks. The experimental transfer learners produce the image features (Inception-v3, VGG-16 net, and VGG-19 net). After that, we use the 10-cross folders SVM classifier with different kernels, such as the radial bias (RBF) function, polynomial, sigmoid, and linear, to classify into three categories that are benign, malignant, and normal. According to our observations, the Inception-v3 transfer learner produces quality features for classification. Its classification accuracy is higher than that of other transfer learners classified by the SVM with all kernels. Interestingly, the SVM polynomial kernel performs better for all features of transfer learning than the remaining SVM kernels. According to our findings, the Inception-v3+SVM (polynomial) performance is very high, with a 0.944 AUC and 87.44% classification accuracy, higher than other experimental models.

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[1] “Breast cancer overview: Causes, symptoms, signs, stages & types,” Cleveland Clinic. [Online]. Available: https://my.clevelandclinic.org/health/diseases/3986-breast-cancer . [Accessed: 14-Dec-2022] [2] Breast cancer (2022) World Health Organization. World Health Organization. Available at: https://www.who.int/news-room/fact-sheets/detail/breast-cancer (Accessed: December 14, 2022). [3] J. Seladi-Schulman, “Breast cancer survival rates: By stage, demographics, and more,” Healthline, 04-Feb-2022. [Online]. Available: https://www.healthline.com/health/breast-cancer/survival-facts-statistics#about-the-numbers . [Accessed: 14-Jan-2022] [4] Sivarajah, R. T., Brown, K., & Chetlen, A. (2020). “I can see clearly now.” fundamentals of breast ultrasound optimization. Clinical Imaging, 64, 124-135. DOI: https://doi.org/10.1016/j.clinimag.2020.03.012 [5] Raja, G. B. (2022). Early detection of breast cancer using efficient image processing algorithms and prediagnostic techniques: A detailed approach. In Cognitive Systems and Signal Processing in Image Processing (pp. 223-251). Academic Press.DOI: https://doi.org/10.1016/B978-0-12-824410-4.00009-X [6] Yurttakal, A. H., Erbay, H., İkizceli, T., & Karaçavuş, S. (2020). Detection of breast cancer via deep convolution neural networks using MRI images. Multimedia Tools and Applications, 79, 15555-15573. https://doi.org/10.1007/s11042-019-7479-6 [7] Kang, S. Y., Kim, Y. S., Kim, Z., Kim, H. Y., Kim, H. J., Park, S., ... & Korean Breast Cancer Society. (2020). Breast cancer statistics in Korea in 2017: data from a breast cancer registry. Journal of Breast Cancer, 23(2), 115. doi: 10.4048/jbc.2020.23.e24 [8] Balic, M., Thomssen, C., Würstlein, R., Gnant, M., & Harbeck, N. (2019). St. Gallen/Vienna 2019: a brief summary of the consensus discussion on the optimal primary breast cancer treatment. Breast Care, 14(2), 103-110. DOI: https://doi.org/10.1159/000499931 [9] Vicini, F. A., Cecchini, R. S., White, J. R., Arthur, D. W., Julian, T. B., Rabinovitch, R. A., ... & Wolmark, N. (2019). Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial. The Lancet, 394(10215), 2155-2164. DOI: https://doi.org/10.1016/S0140-6736(19)32514-0 [10] Lane, W. O., Thomas, S. M., Blitzblau, R. C., Plichta, J. K., Rosenberger, L. H., Fayanju, O. M., ... & Greenup, R. A. (2019). Surgical resection of the primary tumor in women with de novo stage IV breast cancer: contemporary practice patterns and survival analysis. Annals of surgery, 269(3), 537.doi: 10.1097/SLA.0000000000002621 [11] Alsolami, A. S., Shalash, W., Alsaggaf, W., Ashoor, S., Refaat, H., & Elmogy, M. (2021). King Abdulaziz University Breast Cancer Mammogram Dataset (KAU-BCMD). Data, 6(11), 111. https://doi.org/10.3390/data6110111 [12] Zhu, W., Xie, L., Han, J., & Guo, X. (2020). The application of deep learning in cancer prognosis prediction. Cancers, 12(3), 603. doi:10.3390/cancers12030603 [13] Tufail, A. B., Ma, Y. K., Kaabar, M. K., Martínez, F., Junejo, A. R., Ullah, I., & Khan, R. (2021). Deep learning in cancer diagnosis and prognosis prediction: a minireview on challenges, recent trends, and future directions. Computational and Mathematical Methods in Medicine, 2021. https://doi.org/10.1155/2021/9025470 [14] Kourou, K., Exarchos, K. P., Papaloukas, C., Sakaloglou, P., Exarchos, T., & Fotiadis, D. I. (2021). Applied machine learning in cancer research: A systematic review for patient diagnosis, classification and prognosis. Computational and Structural Biotechnology Journal, 19, 5546-5555. https://doi.org/10.1016/j.csbj.2021.10.006 [15] Tang, Binhua, Zixiang Pan, Kang Yin, and Asif Khateeb. "Recent advances of deep learning in bioinformatics and computational biology." Frontiers in genetics 10 (2019): 214. doi: 10.3389/fgene.2019.00214 [16] Lee, C. H., Dershaw, D. D., Kopans, D., Evans, P., Monsees, B., Monticciolo, D., ... & Burhenne, L. W. (2010). Breast cancer screening with imaging: recommendations from the Society of Breast Imaging and the ACR on the use of mammography, breast MRI, breast ultrasound, and other technologies for the detection of clinically occult breast cancer. Journal of the American college of radiology, 7(1), 18-27. DOI: https://doi.org/10.1016/j.jacr.2009.09.022 [17] Wu, W. J., Lin, S. W., & Moon, W. K. (2012). Combining support vector machine with genetic algorithm to classify ultrasound breast tumor images. Computerized Medical Imaging and Graphics, 36(8), 627-633. DOI: http://dx.doi.org/10.1016/j.compmedimag.2012.07.004 [18] Houssein, E. H., Emam, M. M., Ali, A. A., & Suganthan, P. N. (2021). Deep and machine learning techniques for medical imaging-based breast cancer: A comprehensive review. Expert Systems with Applications, 167, 114161. DOI: https://doi.org/10.1016/j.eswa.2020.114161 [19] Rezaei, Z. (2021). A review on image-based approaches for breast cancer detection, segmentation, and classification. Expert Systems with Applications, 182, 115204. DOI: https://doi.org/10.1016/j.eswa.2021.115204 [20] MurtiRawat, R., Panchal, S., Singh, V. K., & Panchal, Y. (2020, July). Breast cancer detection using K-nearest neighbors, logistic regression and ensemble learning. In 2020 international conference on electronics and sustainable communication systems (ICESC) (pp. 534-540). IEEE. DOI: 10.1109/ICESC48915.2020.9155783 [21] Vakanski, A., Xian, M., & Freer, P. E. (2020). Attention-enriched deep learning model for breast tumor segmentation in ultrasound images. Ultrasound in Medicine & Biology, 46(10), 2819-2833. DOI: https://doi.org/10.1016/j.ultrasmedbio.2020.06.015 [22] Luo, Y., Huang, Q., & Li, X. (2022). Segmentation information with attention integration for classification of breast tumor in ultrasound image. Pattern Recognition, 124, 108427. DOI: https://doi.org/10.1016/j.patcog.2021.108427 [23] Fei, X., Zhou, S., Han, X., Wang, J., Ying, S., Chang, C., ... & Shi, J. (2021). Doubly supervised parameter transfer classifier for diagnosis of breast cancer with imbalanced ultrasound imaging modalities. Pattern Recognition, 120, 108139. DOI: https://doi.org/10.1016/j.patcog.2021.108139 [24] B. E. Manjunath Swamy. "Personalized Ranking Mechanism Using Yandex Dataset on Machine Learning Approaches." Proceedings of the International Conference on Cognitive and Intelligent Computing: ICCIC 2021, Volume 1. Singapore: Springer Nature Singapore, 2022. [25] Burada, Sreedhar,"Computer-Aided Diagnosis Mechanism for Melanoma Skin Cancer Detection Using Radial Basis Function Network." Proceedings of the International Conference on Cognitive and Intelligent Computing: ICCIC 2021, Volume 1. Singapore: Springer Nature Singapore, 2022. [26] Kumar, M. S, et al. "Deep Convolution Neural Network Based solution for Detecting Plant Diseases." Journal of Pharmaceutical Negative Results (2022): 464-471. [27] Kumar, M. Sunil, et al. "Deep Convolution Neural Network Based solution for Detecting Plant Diseases." Journal of Pharmaceutical Negative Results (2022): 464-471. [28] Sreedhar, B., BE, M.S. and Kumar, M.S., 2020, October. A comparative study of melanoma skin cancer detection in traditional and current image processing techniques. In 2020 Fourth International Conference on I-SMAC (IoT in Social, Mobile, Analytics and Cloud)(I-SMAC) (pp. 654-658). IEEE. [29] P. Sai Kiran, and M. S Kumar. "Resource aware virtual machine placement in IaaS cloud using bio-inspired firefly algorithm." Journal of Green Engineering 10 (2020): 9315-9327. [30] Balaji, K., P. Sai Kiran, and M. Sunil Kumar. "Power aware virtual machine placement in IaaS cloud using discrete firefly algorithm." Applied Nanoscience (2022): 1-9. [31] Ananthanatarajan, V., Kumar, M. S., & Tamizhazhagan, V. (2020). Forecasting of wind power using lstm recurrent neural network. Journal of Green Engineering, 10. [32] Vesal, S., Ravikumar, N., Davari, A., Ellmann, S., & Maier, A. (2018, June). Classification of breast cancer histology images using transfer learning. In International conference image analysis and recognition (pp. 812-819). Springer, Cham. https://doi.org/10.1007/978-3-319-93000-8_92 [33] Ferreira, C. A., Melo, T., Sousa, P., Meyer, M. I., Shakibapour, E., Costa, P., & Campilho, A. (2018, June). Classification of breast cancer histology images through transfer learning using a pre-trained inception resnet v2. In International conference image analysis and recognition (pp. 763-770). Springer, Cham. https://doi.org/10.1007/978-3-319-93000-8_86