DEVELOPMENT OF ESSENTIAL OIL EXTRACTION TECHNIQUES FOR LONG-TERM ECONOMIC VIABILITY

Main Article Content

Ayush Dangwal1, Kiran Dobhal*1, Manoj Bisht2, Shalini Rawat2, Ruchika Garg3, S.P. Bhatt1, Samiya1

Keywords

Essential oil, Microwave, Ultrasound, Pressure, Supercritical.

Abstract

In the contemporary era, essential oils (EOs) are essential components of consumer demand in form of cleaning reagents, pharmaceuticals, aroma agents, packaged food materials, beverages, soft liqueur, disinfecting & antiseptic agents, & insecticides. Still, the production, quality, & expenditure of EOs are critical in industrial plants. Tradition methods are substantial & applied in many regions of the world for it. The importance of EOs cannot be overstated, as they are more beneficial than synthetic drugs. Non-traditional advanced techniques viz. microwave-assisted extraction, supercritical extraction, ultrasound-assisted extraction, & pressurized liquid extraction are well established to increase the production & quality of EOs. Although these techniques required expertise person, advanced laboratory arrangements, cleaning, & specification. This review explores operational methodologies & the economic aspects of these advanced techniques.

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1. Romo-Rico J, Krishna SM, Bazaka K, Golledge J, Jacob MV. Potential of plant secondary metabolite-based polymers to enhance wound healing. Acta Biomater. 2022;147:34-49. doi:10.1016/j.actbio.2022.05.043 2. Dobhal K, Singh N, Semwal A, Negi A. A brief review on: hazelnuts. Int. J. Recent Sci. Res. 2018;9(1):23680-4. 3. Wolfender JL, Marti G, Thomas A, Bertrand S. Current approaches and challenges for the metabolite profiling of complex natural extracts. J Chromatogr A. 2015;1382:136-164. doi:10.1016/j.chroma.2014.10.091 4. Walker K, Schoendorf A, Croteau R. Molecular cloning of a taxa-4(20),11(12)-dien-5alpha-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli. Arch Biochem Biophys. 2000;374(2):371-380. doi:10.1006/abbi.1999.1609 5. Rehman SU, Choe K, Yoo HH. Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules. 2016;21(3):331. Published 2016 Mar 10. doi:10.3390/molecules21030331 6. Sommano SR, Chittasupho C, Ruksiriwanich W, Jantrawut P. The Cannabis Terpenes. Molecules. 2020;25(24):5792. Published 2020 Dec 8. doi:10.3390/molecules25245792 7. Vigan M. Essential oils: renewal of interest and toxicity. Eur J Dermatol. 2010;20(6):685-692. doi:10.1684/ejd.2010.1066 8. Mercier B, Prost J, Prost M. The essential oil of turpentine and its major volatile fraction (alpha- and beta-pinenes): a review. Int J Occup Med Environ Health. 2009;22(4):331-342. doi:10.2478/v10001-009-0032-5 9. Zhang Y, Long Y, Yu S, et al. Natural volatile oils derived from herbal medicines: A promising therapy way for treating depressive disorder. Pharmacol Res. 2021;164:105376. doi:10.1016/j.phrs.2020.105376 10. Wang L, Zhang Y, Fan G, Ren JN, Zhang LL, Pan SY. Effects of orange essential oil on intestinal microflora in mice. J Sci Food Agric. 2019;99(8):4019-4028. doi:10.1002/jsfa.9629 11. Ramola B, Kumar V, Nanda M, Mishra Y, Tyagi T, Gupta A, Sharma N. Evaluation, comparison of different solvent extraction, cell disruption methods and hydrothermal liquefaction of Oedogonium macroalgae for biofuel production. Biotechnology Reports. 2019 Jun 1;22:e00340. 12. Rodman CP. Sassafras. J Clin Oncol. 2020;38(2):169-170. doi:10.1200/JCO.19.01839 13. Gruenwald J, Freder J, Armbruester N. Cinnamon and health. Crit Rev Food Sci Nutr. 2010;50(9):822-834. doi:10.1080/10408390902773052 14. Peruč D, Tićac B, Broznić D, Gobin I. Juniper and immortelle essential oils synergistically inhibit adhesion of nontuberculous mycobacteria to Acanthamoeba castellanii. Arh Hig Rada Toksikol. 2020;71(3):223-230. Published 2020 Oct 6. doi:10.2478/aiht-2020-71-3442 15. Haro-González JN, Castillo-Herrera GA, Martínez-Velázquez M, Espinosa-Andrews H. Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health. Molecules. 2021;26(21):6387. Published 2021 Oct 22. doi:10.3390/molecules26216387 16. Butt MS, Pasha I, Sultan MT, Randhawa MA, Saeed F, Ahmed W. Black pepper and health claims: a comprehensive treatise. Crit Rev Food Sci Nutr. 2013;53(9):875-886. doi:10.1080/10408398.2011.571799 17. Jasmine. In: Drugs and Lactation Database (LactMed). Bethesda (MD): National Institute of Child Health and Human Development; May 17, 2021. 18. Cavanagh HM, Wilkinson JM. Biological activities of lavender essential oil. Phytother Res. 2002;16(4):301-308. doi:10.1002/ptr.1103 19. Chamomile. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; May 24, 2022. 20. Moss M, Hewitt S, Moss L, Wesnes K. Modulation of cognitive performance and mood by aromas of peppermint and ylang-ylang. Int J Neurosci. 2008;118(1):59-77. doi:10.1080/00207450601042094 21. Geranium. In: Drugs and Lactation Database (LactMed). Bethesda (MD): National Institute of Child Health and Human Development; June 21, 2021. 22. Saporito F, Sandri G, Bonferoni MC, et al. Essential oil-loaded lipid nanoparticles for wound healing. Int J Nanomedicine. 2017;13:175-186. Published 2017 Dec 27. doi:10.2147/IJN.S152529 23. Nauman MC, Johnson JJ. Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers. Integr Food Nutr Metab. 2019;6(2):10.15761/IFNM.1000249. doi:10.15761/IFNM.1000249 24. Juranović-Cindrić I, Zeiner M, Starčević A, et al. Influence of F1 hybridization on the metal uptake behaviour of pine trees (Pinus nigra x Pinus thunbergiana; Pinus thunbergiana x Pinus nigra). J Trace Elem Med Biol. 2018;48:190-195. doi:10.1016/j.jtemb.2018.04.009 25. Sakkas H, Papadopoulou C. Antimicrobial Activity of Basil, Oregano, and Thyme Essential Oils. J Microbiol Biotechnol. 2017;27(3):429-438. doi:10.4014/jmb.1608.08024 26. McKay DL, Blumberg JB. A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.). Phytother Res. 2006;20(8):619-633. doi:10.1002/ptr.1936 27. Sakkas H, Papadopoulou C. Antimicrobial Activity of Basil, Oregano, and Thyme Essential Oils. J Microbiol Biotechnol. 2017;27(3):429-438. doi:10.4014/jmb.1608.08024 28. Greenwalt CJ, Steinkraus KH, Ledford RA. Kombucha, the fermented tea: microbiology, composition, and claimed health effects. J Food Prot. 2000;63(7):976-981. doi:10.4315/0362-028x-63.7.976 29. Geranium. In: Drugs and Lactation Database (LactMed). Bethesda (MD): National Institute of Child Health and Human Development; June 21, 2021. 30. Luo B, Kastrat E, Morcol T, Cheng H, Kennelly E, Long C. Gaultheria longibracteolata, an alternative source of wintergreen oil. Food Chem. 2021;342:128244. doi:10.1016/j.foodchem.2020.128244 31. Pennyroyal Oil. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; March 28, 2020. 32. Lee J, Kong B, Lee SH. Patchouli Alcohol, a Compound from Pogostemon cablin, Inhibits Obesity. J Med Food. 2020;23(3):326-334. doi:10.1089/jmf.2019.0182 33. Raveau R, Lounès-Hadj Sahraoui A, Hijri M, Fontaine J. Clary Sage Cultivation and Mycorrhizal Inoculation Influence the Rhizosphere Fungal Community of an Aged Trace-Element Polluted Soil. Microorganisms. 2021;9(6):1333. Published 2021 Jun 19. doi:10.3390/microorganisms9061333 34. Hesabi Nameghi A, Edalatian O, Bakhshalinejad R. Effects of a blend of thyme, peppermint and eucalyptus essential oils on growth performance, serum lipid and hepatic enzyme indices, immune response and ileal morphology and microflora in broilers. J Anim Physiol Anim Nutr (Berl). 2019;103(5):1388-1398. doi:10.1111/jpn.13122 35. Grant P. Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. A randomized controlled trial. Phytother Res. 2010;24(2):186-188. doi:10.1002/ptr.2900 36. Rombolà L, Tridico L, Scuteri D, et al. Bergamot Essential Oil Attenuates Anxiety-Like Behaviour in Rats. Molecules. 2017;22(4):614. Published 2017 Apr 11. doi:10.3390/molecules22040614 37. Scurria A, Sciortino M, Albanese L, et al. Flavonoids in Lemon and Grapefruit IntegroPectin*. ChemistryOpen. 2021;10(10):1055-1058. doi:10.1002/open.202100223 38. Ayati Z, Amiri MS, Ramezani M, Delshad E, Sahebkar A, Emami SA. Phytochemistry, Traditional Uses and Pharmacological Profile of Rose Hip: A Review. Curr Pharm Des. 2018;24(35):4101-4124. doi:10.2174/1381612824666181010151849 39. Mercier B, Prost J, Prost M. The essential oil of turpentine and its major volatile fraction (alpha- and beta-pinenes): a review. Int J Occup Med Environ Health. 2009;22(4):331-342. doi:10.2478/v10001-009-0032-5 40. Lakhan SE, Ford CT, Tepper D. Zingiberaceae extracts for pain: a systematic review and meta-analysis. Nutr J. 2015;14:50. Published 2015 May 14. doi:10.1186/s12937-015-0038-8 41. Kocaadam B, Şanlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit Rev Food Sci Nutr. 2017;57(13):2889-2895. doi:10.1080/10408398.2015.1077195 42. Kaur A, Bhatti R. Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components. Phytother Res. 2021;35(11):5961-5979. doi:10.1002/ptr.7206 43. Li JN, Henning SM, Thames G, et al. Almond consumption increased UVB resistance in healthy Asian women. J Cosmet Dermatol. 2021;20(9):2975-2980. doi:10.1111/jocd.13946 44. Barceloux DG. Nutmeg (Myristica fragrans Houtt.). Dis Mon. 2009;55(6):373-379. doi:10.1016/j.disamonth.2009.03.007 45. Campos JR, Severino P, Ferreira CS, et al. Linseed Essential Oil - Source of Lipids as Active Ingredients for Pharmaceuticals and Nutraceuticals. Curr Med Chem. 2019;26(24):4537-4558. doi:10.2174/0929867325666181031105603 46. Yao D, Zhang B, Zhu J, et al. Advances on application of fenugreek seeds as functional foods: Pharmacology, clinical application, products, patents and market. Crit Rev Food Sci Nutr. 2020;60(14):2342-2352. doi:10.1080/10408398.2019.1635567 47. Anise. In: Drugs and Lactation Database (LactMed). Bethesda (MD): National Institute of Child Health and Human Development; March 21, 2022. 48. Portincasa P, Bonfrate L, Scribano ML, et al. Curcumin and Fennel Essential Oil Improve Symptoms and Quality of Life in Patients with Irritable Bowel Syndrome. J Gastrointestin Liver Dis. 2016;25(2):151-157. doi:10.15403/jgld.2014.1121.252.ccm 49. Cumin. In: Drugs and Lactation Database (LactMed). Bethesda (MD): National Institute of Child Health and Human Development; January 18, 2022. 50. Charpin D, Pichot C, Belmonte J, et al. Cypress Pollinosis: from Tree to Clinic. Clin Rev Allergy Immunol. 2019;56(2):174-195. doi:10.1007/s12016-017-8602-y 51. Tan CS, Isa NM, Ismail I, Zainal Z. Agarwood Induction: Current Developments and Future Perspectives. Front Plant Sci. 2019;10:122. Published 2019 Feb 7. doi:10.3389/fpls.2019.00122 52. Sokolova AS, Kovaleva KS, Yarovaya OI, et al. (+)-Camphor and (-)-borneol derivatives as potential anti-orthopoxvirus agents. Arch Pharm (Weinheim). 2021;354(6):e2100038. doi:10.1002/ardp.202100038 53. Moy RL, Levenson C. Sandalwood Album Oil as a Botanical Therapeutic in Dermatology. J Clin Aesthet Dermatol. 2017;10(10):34-39. 54. de Almeida RN, Araújo DA, Gonçalves JC, et al. Rosewood oil induces sedation and inhibits compound action potential in rodents. J Ethnopharmacol. 2009;124(3):440-443. doi:10.1016/j.jep.2009.05.044 55. Sühring R, Chen CE, McLachlan MS, MacLeod M. Bioconcentration of cedarwood oil constituents in rainbow trout. Environ Sci Process Impacts. 2021;23(5):689-698. doi:10.1039/d1em00009h 56. de Groot AC, Schmidt E. Essential Oils, Part I: Introduction. Dermatitis. 2016;27(2):39-42. doi:10.1097/DER.0000000000000175 57. Aziz ZAA, Ahmad A, Setapar SHM, et al. Essential Oils: Extraction Techniques, Pharmaceutical And Therapeutic Potential - A Review. Curr Drug Metab. 2018;19(13):1100-1110. doi:10.2174/1389200219666180723144850 58. Razola-Díaz MDC, Guerra-Hernández EJ, García-Villanova B, Verardo V. Recent developments in extraction and encapsulation techniques of orange essential oil. Food Chem. 2021;354:129575. doi:10.1016/j.foodchem.2021.129575 59. Bagade SB, Patil M. Recent Advances in Microwave Assisted Extraction of Bioactive Compounds from Complex Herbal Samples: A Review. Crit Rev Anal Chem. 2021;51(2):138-149. doi:10.1080/10408347.2019.1686966 60. Akhtar I, Javad S, Yousaf Z, Iqbal S, Jabeen K. Review: Microwave assisted extraction of phytochemicals an efficient and modern approach for botanicals and pharmaceuticals. Pak J Pharm Sci. 2019;32(1):223-230. 61. Zhao JL, Zhang M, Zhou HL. Microwave-Assisted Extraction, Purification, Partial Characterization, and Bioactivity of Polysaccharides from Panax ginseng. Molecules. 2019;24(8):1605. Published 2019 Apr 23. doi:10.3390/molecules24081605 62. Wrona O, Rafińska K, Możeński C, Buszewski B. Supercritical Fluid Extraction of Bioactive Compounds from Plant Materials. J AOAC Int. 2017;100(6):1624-1635. doi:10.5740/jaoacint.17-0232 63. Uwineza PA, Waśkiewicz A. Recent Advances in Supercritical Fluid Extraction of Natural Bioactive Compounds from Natural Plant Materials. Molecules. 2020;25(17):3847. Published 2020 Aug 24. doi:10.3390/molecules25173847 64. Pourmortazavi SM, Hajimirsadeghi SS. Supercritical fluid extraction in plant essential and volatile oil analysis. J Chromatogr A. 2007;1163(1-2):2-24. doi:10.1016/j.chroma.2007.06.021 65. Karbuz P, Tugrul N. Microwave and ultrasound assisted extraction of pectin from various fruits peel. J Food Sci Technol. 2021;58(2):641-650. doi:10.1007/s13197-020-04578-0 66. Dias ALB, de Aguiar AC, Rostagno MA. Extraction of natural products using supercritical fluids and pressurized liquids assisted by ultrasound: Current status and trends. Ultrason Sonochem. 2021;74:105584. doi:10.1016/j.ultsonch.2021.105584 67. Egüés I, Hernandez-Ramos F, Rivilla I, Labidi J. Optimization of Ultrasound Assisted Extraction of Bioactive Compounds from Apple Pomace. Molecules. 2021;26(13):3783. Published 2021 Jun 22. doi:10.3390/molecules26133783 68. Liang X, Nielsen NJ, Christensen JH. Selective pressurized liquid extraction of plant secondary metabolites: Convallaria majalis L. as a case. Anal Chim Acta X. 2020;4:100040. Published 2020 Feb 24. doi:10.1016/j.acax.2020.100040 69. Santos PH, Kammers JC, Silva AP, Oliveira JV, Hense H. Antioxidant and antibacterial compounds from feijoa leaf extracts obtained by pressurized liquid extraction and supercritical fluid extraction. Food Chem. 2021;344:128620. doi:10.1016/j.foodchem.2020.128620 70. Titaley IA, Eriksson U, Larsson M. Rapid extraction method of polycyclic aromatic compounds in soil using basic silica selective pressurized liquid extraction. J Chromatogr A. 2020;1618:460896. doi:10.1016/j.chroma.2020.460896 71. Waseem R, Low KH. Advanced analytical techniques for the extraction and characterization of plant-derived essential oils by gas chromatography with mass spectrometry. J Sep Sci. 2015;38(3):483-501. doi:10.1002/jssc.201400724 72. Filly A, Fernandez X, Minuti M, Visinoni F, Cravotto G, Chemat F. Solvent-free microwave extraction of essential oil from aromatic herbs: from laboratory to pilot and industrial scale. Food Chem. 2014;150:193-198. doi:10.1016/j.foodchem.2013.10.139 73. Hensel A, Bauer R, Heinrich M, et al. Challenges at the Time of COVID-19: Opportunities and Innovations in Antivirals from Nature. Planta Med. 2020;86(10):659-664. doi:10.1055/a-1177-4396 74. Olalere O A, Gan C, Adeyi O, Taiwo A E, Olaiya F G, et al. Upscalability and Techno-economic Perspectives of Nonconventional Essential Oils Extraction Techniques. Jundishapur J Nat Pharm Prod.17(3):e122792. doi: 10.5812/jjnpp-122792. 75. Bai D, Li X, Wang S, et al. Advances in extraction methods, chemical constituents, pharmacological activities, molecular targets and toxicology of volatile oil from Acorus calamus var. angustatus Besser. Front Pharmacol. 2022;13:1004529. Published 2022 Dec 1. doi:10.3389/fphar.2022.1004529 76. Douglas JM. Conceptual design of chemical processes. 1110. New York, USA: McGraw-Hill; 1988. 77. Turton R, Bailie RC, Whiting WB, Shaeiwitz JA. Analysis, synthesis and design of chemical processes. New Jersey, USA: Pearson Prentice Hall; 2014