CLINICO-ETIOLOGICAL PROFILE OF PERSISTENT PNEUMONIA IN CHILDREN AGED 2 MONTHS TO 12 YEARS IN A TERTIARY CARE HOSPITAL.
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Keywords
Persistent Pneumonia;GERD; Tuberculosis
Abstract
Abstract Background: Pneumonia is the most common cause of childhood morbidity and mortality in developing countries, especially in those younger than 5 years of age. This study was conducted to evaluate the clinical and etiological profile of persistent pneumonia to evaluate immediate outcome of Persistent Pneumonia in these children.
Materials and Methods: 59 hospitalized children with persistent pneumonia were evaluated for clinical and etiological profile and its immediate outcome.
Results: Out of 59 children, In the present study, among the study population, GERD was the most common cause of persistent pneumonia (18.64%), followed by Tuberculosis (16.95%), CMV pneumonia (13.56%). Congenital heart disease was present in 10.17%,HIV in 8.47%, Floppy infant syndrome in 6.78%. Auto immune diseases, Gram negative infestations, bronchiectasis was contributed by 5.08% each. 3.39% each was contributed by CCAM, FB aspiration. 1.69% was contributed by cystic lung and interstitial lung disease.As far as the clinical profile was concerned, out of 59 children, Cough and respiratory distress was present among all the patients. Fever was present in 86.44%, weight loss in 52.54%, nasal regurgitation in 22.03%. SRS cycle and diarrhea was present in 10.17%.
Conclusions: The common underlying etiologies of persistent pneumonia in children found in our study were aspiration syndromes followed by pulmonary tuberculosis, congenital heart disease (CHD), immunodeficiency and bronchiectasis.
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References
1. WHO | Child mortality and causes of death. WHO. Accessed on 4 December 2022.
2. K Park. Textbook of Preventive and Social Medicine Epidemiology of Communicable disease, 25th editionpg 180
3. Surviving the first five years of life. The world health report. WHO 2003.chapter 1:1-22
4. Kyprianou A, Hall CS. The challenge of nonresolving pneumonia: Knowing the norms of radiographic resolution is the key. Postgraduate medicine 2003; 113:42-90.
5. Menendez R, Torres T. Nonresponding Pneumonia. Clin Pulm Med 2004;11: 298–306
6. Manish Kumar, Niranjan Biswal, V. Bhuvaneswari1 and S. Srinivasan .Persistent Pneumonia: Underlying Cause and Outcome November 2009 The Indian Journal of Pediatrics 76(12):1223-6
7. Meena H M, Gothwal S, Choudhary R, Clinico-etiological profile of persistent pneumonia in children: An observational study at a tertiary care hospital. IP Indian J Immunol Respir Med 2016;1(4):93-96
8. Lodha R, Puranik M, Chandra U, Natchu M, Kabra SK. Persistent pneumonia in children. Indian Pediatr. 2003; 40:67–70.
9. Selwyn BJ on behalf of the Coordinated Data Group of the BOSTID Researchers. The epidemiology of acute respiratory tract infections in young children: Comparison of findings from several developing countries. Rev Infect Dis 1990; 12 (Suppl 8): S870-S888.
10. Pio A, Leowski J, Ten Dam HG. The magnitude of the problems of acute respiratory infections. In: Acute Respiratory Infections in Childhood. Eds Douglas M, Kerby-Eaton E. Proceedings of an International Workshop, Sydney, Australia, August 1984, University of Adelaide, 1984; 3-17.
11. Wald ER. Recurrent and non-resolving pneumonia in children. Semin Respir Infect 1993; 8: 46-58.
12. Obsorne D. The radiologic appearance of viral disease of the lower respiratory tract in infants and young children. Am J Roentgenol 1978; 130: 29-33.
13. Osborne D, White P. Radiology of epidemic adenovirus-21 infection of the lower respiratory tract in infants and young children. Am J Roentgenol 1979; 133: 397-400.
14. Jay SJ, Johanson WG, Pierce AK. The radiographic resolution of Streptococcus pneumonia. N Engl J Med 1975; 293: 798-801.
15. Belessis Y, Doyle K, Jaffe A. Investigation of a child with recurrent pneumonia. Medicine Today 2008; 9:16–26.
16. Couriel J. Assessment of the child with recurrent chest infections. Br Med Bull 2002; 61:115–32.
17. Avenant T. Recurrent or Persistent Pneumonia n.d. http://www.ais.up.ac.za/health/blocks/block7/persistentpneumonia.pdf
18. Eigen H, Laughlin JJ, Homrighausen J. Recurrent Pneumonia in Children and Its Relationship to Bronchial Hyperreactivity. Pediatrics 1982; 70:698–704.
19. Li H, Jiang Z, Jiang Q, et al. Underlying illnesses and diagnosis of recurrent pneumonia in children. Chinese Journal of Practical Pediatrics 2004-03
20. Campbell DM, Wang EE. Underlying Causes of Recurrent Pneumonia in Children. Arch PediatrAdolesc Med 2000; 154:190–194.
21. Lodha R, Puranik M, Natchu UCM, Kabra SK. Recurrent pneumonia in children: clinical profile and underlying causes. Acta Paediatr 2002; 91:1170–3.
22. Frossard PM, Lestringant G, Girodon E, Goossens M, Dawson KP. Determination of the prevalence of cystic fibrosis in the United Arab Emirates by genetic carrier screening. Clin Genet 1999; 55:496–7.
23. Abdul Wahab A, Al Thani G, Dawod ST, Kambouris M, Al Hamed M. Heterogeneity of the cystic fibrosis phenotype in a large kindred family in Qatar with cystic fibrosis mutation (I1234V). J Trop Pediatr 2001; 47:110–2.
24. Adam KA. Hyposkillia: A Sign of sagging medical profession – A pediatric perspective. Sudan J paediatr 2014; 14(1):11–20
25. Bolursaz MR, Lotfian F, Ghaffaripour HA, Hassanzad M. Underlying causes of Persistent Pneumonia in Children at Pulmonary Referral hospital in Tehran, Iran. Arch Iran Med. 2017; 20(5): 266 – 269.
26. Khaled Saad, Sherif A. Mohamed, Kotb A. Metwalley. Recurrent/Persistent Pneumonia among Children in Upper Egypt. Mediterr J Hematol Infect Dis. 2013; 5(1):e2013028.
27. Kumar M, Biswal N, Bhuvaneswari V, Srinivasan S. Persistent Pneumonia: Underlying Cause and Outcome. Indian J Pediatr. 2009; 76: 1223 – 1226.
28. Meena HM, Gothwal S, Chaudary R. Clinico-etiological profile of persistent pneumonia in children: An observational study at a tertiary care hospital. Indian Journal of Immunology and Respiratory Medicine, October-December 2016;1(4):93-96
29. Lodha R, Puranik M, Chandra U, Natchu M, Kabra SK. Persistentpneumonia in children. Indian Pediatr. 2003; 40: 967 – 970.
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