RECENT ADVANCEMENT OF BIOACTIVE COMPOSITE COATED TITANIUM FOR BIOMEDICAL APPLICATIONS

Main Article Content

Dr Syeda Jeelani Basri1, Dr.Aruna.M2, Ajay Singh SarthI3 , Ishwari Choudhary4, Dillip Narayan Sahu5*, Dr. Dhondiram Tukaram Sakhare6

Keywords

Titanium, stainless steel, Surgeries, Chitosan, Young's modulus and alloy

Abstract

The growth in senior population has led to a rising need for greater quality of life promoting utilisation of implant materials. The requirement in procedures such as hip replacement, knee replacement, etc., is predicted to witness a manifold growth in future. The essential need of any implant (Ti, Mg, Steel, etc) is to operate effectively inside the human body for the desired application i.e., the implant material and the tissue environment of the body should not endure any unwanted or poisonous consequence. Titanium (Ti) and its alloys are frequently utilised as implant materials owing to their outstanding biocompatibility, strength, corrosion resistance and longevity compared to other alloys such as 316, 316L stainless steel, Mg and Co-Cr steels. Nevertheless, Ti and its alloys are bio-inert in nature. The inclusion of Ti in the body as implant material is followed with stress shielding effect at the implant interface owing to its difference in mechanical characteristics compared to the host bones. The mismatch between the Young's modulus of Ti implant and host bones produces adverse resorptive bone remodelling, wearing, loosening and thus failure of the implant. Additionally, the bio-inert Ti surfaces are not adequately bioactive and so surface modification is necessary to promote the bioactivity and osseo integration with bone tissues. The primary objective of this work is to develop PPy bioactive composite coating by incorporating Chitosan (CHI) and Graphene oxide (GO) in PPy matrix using electrical and chemical methods for enhancing the biocompatibility and augmentation of the corrosion resistance property of Ti for biomedical applications.

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References


1. Ansari, R 006, ‘Polypyrrole conducting electroactive polymers: Synthesis and stability studies’, E-Journal of Chemistry, vol. 3, no. 13, pp. 186-201. 2. shassi, SH & agheri, R 014, ‘Sonoelectrochemical and Electrochemical Synthesis of Polypyrrole Films on St-12 Steel and Their Corrosion and Morphological Studies. Advances in Polymer Technology, vol. 33, no. 3, pp. 21419. 3. Bakhsheshi, RH, Hamzah, E, Kasiri, AM, Saud, SN, Yaghoubidoust, F & kbari, E 016, ‘Structure, corrosion behavior, and antibacterial properties of nano-silica/graphene oxide coating on biodegradable magnesium alloy for biomedical applications’, Vacuum, vol. 1 1, pp. 106-110. 4. Bolat, G, Mareci, D, Iacoban, S, Cimpoesu, N & Munteanu, C 2012, ‘The estimation of corrosion behavior of NiTi and NiTiNb alloys using dynamic electrochemical impedance spectroscopy’, Journal of Spectroscopy, vol. 2013. 5. Bora, & Dolui, SK 01 , ‘ abrication of polypyrrole graphene oxide nanocomposites by liquid/liquid interfacial polymerization and evaluation of their optical, electrical and electrochemical properties’, Polymer, vol. 53, no. 4, pp. 923-932. 6. assagneau, T, Guérin, & endler, JH 000, ‘Preparation and characterization of ultrathin films layer-by-layer self-assembled from graphite oxide nanoplatelets and polymers’, Langmuir, vol. 16, no. 18, pp. 7318-7324. 7. Cui, X, Wiler, J, Dzaman, M, ltschuler, R & Martin, D 00 , ‘In vivo studies of polypyrrole peptide coated neural probes’, iomaterials, vol. 24, no. 5, pp. 777-787. 8. Deng, M, Yang, X, Silke, M, Qiu, W, Xu, M, Borghs, G & Chen, H 011, ‘Electrochemical deposition of polypyrrole graphene oxide composite on microelectrodes towards tuning the electrochemical properties of neural probes’, Sensors and ctuators : hemical, vol. 158, no. 1, pp. 176-184. 9. Elieh- li, KD & Hamblin, MR 016, ‘ hitin and chitosan: production and application of versatile biomedical nanomaterials’, International Journal of Advanced Research, vol. 4, no. 3, pp. 411. 10. Gebhardt, F, Seuss, S, Turhan, M, Hornberger, H, Virtanen, S & occaccini, R 01 , ‘ haracterization of electrophoretic chitosan coatings on stainless steel’, Materials letters, vol. 66, no. 1, pp. 0 -304. 11. Goenka, S, Sant, V & Sant, S 014, ‘Graphene-based nanomaterials for drug delivery and tissue engineering’, Journal of ontrolled Release, vol. 173, pp. 75-88. 12. Hamai, R, Shirosaki, Y & Miyazaki, T 017, ‘ patite formation on a hydrogel containing sulfinic acid group under physiological conditions’, Journal of Biomedical Materials Research Part B: Applied Biomaterials, vol. 105, no. 7, pp. 1924-1929. 13. Hanawa, T 2012, ‘Research and development of metals for medical devices based on clinical needs’, Science and Technology of dvanced Materials, vol. 13, no. 6, pp. 064102. 14. Indira, K, Mudali, UK, Nishimura, T & Rajendran, N 015, ‘ review on TiO2 nanotubes: influence of anodization parameters, formation mechanism, properties, corrosion behavior, and biomedical applications’, Journal of Bio-and Tribo-Corrosion, vol. 1, no. 4, pp. 1-28. 15. Konwer, S, oruah, R & Dolui, SK 011, ‘Studies on conducting polypyrrole graphene oxide composites as supercapacitor electrode’, Journal of electronic materials, vol. 40, no. 11, pp. 2248-2255. 16. Kulshrestha, S, Khan, S, Meena, R, Singh, R & Khan, U 014, ‘ graphene/zinc oxide nanocomposite film protects dental implant surfaces against cariogenic Streptococcus mutans’, iofouling, vol. 0, no. 10, pp. 1281-1294. 17. Mike, J & Lutkenhaus, JL 01 , ‘Recent advances in conjugated polymer energy storage’, Journal of Polymer Science Part : Polymer Physics, vol. 51, no. 7, pp. 468-480. 18. Nakamura, N, Wu, Y, Yokoshima, T, Nara, H, Momma, T & Osaka, T 016, ‘ ilm properties of electropolymerized polypyrrole for a sulfur/Ketjenblack cathode in lithium secondary batteries’, Journal of The Electrochemical Society, vol. 163, no. 5, pp. A683-A689. 19. Orlikowski, J & Darowicki, K 011, ‘Investigations of pitting corrosion of magnesium by means of DEIS and acoustic emission’, Electrochimica Acta, vol. 56, no. 23, pp. 7880-7884. 20. Poinern, GEJ, rundavanam, RK & awcett, D 01 , ‘Nanometre scale hydroxyapatite ceramics for bone tissue engineering’, merican Journal of Biomedical Engineering, vol. 3, no. 6, pp. 148-168.