@article{Canatan_Vives Corrons_De Sanctis_2020, title={The Multifacets of COVID-19 in Adult Patients: A Concise Clinical Review on Pulmonary and Extrapulmonary Manifestations for Healthcare Physicians: Covid-19 and Pulmonary and Extrapulmonary Manifestations }, volume={91}, url={https://mattioli1885journals.com/index.php/actabiomedica/article/view/10665}, DOI={10.23750/abm.v91i4.10665}, abstractNote={<p><strong> Summary.</strong> COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Most people with COVID-19 have a mild to moderate respiratory illness; others experience severe illness, such as COVID-19 pneumonia. The first and most accessible diagnostic information is from symptoms and signs from clinical examination. Infected patients present with a variety of manifestations. Formal diagnosis requires laboratory analysis of nose and throat samples, or imaging tests like CT scans. Emerging data suggest that coronavirus disease 2019 (COVID-19) has extrapulmonary manifestations. Sometimes these extra-respiratory manifestations may be the initial or only symptom of COVID-19, prior to fever or respiratory manifestations. In summary, our concise review shows that there is a wide range of symptoms that can be presented by COVID-19 patients. Extra-respiratory manifestations of SARS-CoV-2 infection have recently been observed in the rapidly increasing number of COVID-19 cases. Considering the broad spectrum of clinical manifestations and the increasing worldwide burden of the disease, there is an urgent need to rapidly scale up the diagnostic capacity to detect COVID-19 and its complications.</p>}, number={4}, journal={Acta Biomedica Atenei Parmensis}, author={Canatan , Duran and Vives Corrons, Joan Lluis and De Sanctis, Vincenzo}, year={2020}, month={Nov.}, pages={e2020173} }