@article{Orso_Mattuzzi_Scapol_Delrio_Vetrugno_Bove_2021, title={Phlegmasia cerulea dolens superimposed on disseminated intravascular coagulation in COVID-19.: Phlegmasia and disseminated intravascular coagulation in COVID-19.}, volume={92}, url={https://mattioli1885journals.com/index.php/actabiomedica/article/view/11478}, DOI={10.23750/abm.v92i4.11478}, abstractNote={<p align="JUSTIFY"><span style="color: #0e101a;"><span style="font-size: medium;">COVID-19 infection has several cardiovascular implications, and coagulopathy is a common abnormality in these patients, often coupled with elevated plasma fibrinogen and D-dimer levels, contributing to adverse outcomes. Phlegmasia cerulea dolens (PCD) is a rare manifestation of deep vein thrombosis. It is life-threatening and can rapidly lead to venous gangrene of the extremity. Only a few cases of COVID-19 associated with PCD are reported in the literature, despite thromboembolism being the common paradigm between the two diseases. We present the case of a 64-year-old adult with acute severe COVID-19 pneumonia who developed PCD despite constantly elevated activated partial thromboplastin time and international normalized ratio.</span></span></p>}, number={4}, journal={Acta Biomedica Atenei Parmensis}, author={Orso, Daniele and Mattuzzi, Lisa and Scapol, Sara and Delrio, Silvia and Vetrugno, Luigi and Bove, Tiziana}, year={2021}, month={Sep.}, pages={e2021101} }