@article{Internò_Rudà_Sergi_Soffietti_Porta_2022, title={Newly diagnosed Glioblastoma Multiforme (GBM) during COVID-19 pandemic: changes in therapeutic approach to minimize in-hospital SARS-COV-2 contagion in pre-vaccine era}, volume={93}, url={https://mattioli1885journals.com/index.php/actabiomedica/article/view/12452}, DOI={10.23750/abm.v93i3.12452}, abstractNote={<p>COVID-19 pandemic revolutionized the way in which cancer patients are treated worldwide. Regarding neuro-oncological patients, usually considered frail and with lower life-expectancy in respect to other oncological patients, the international scientific community had to urgently reorganize the treatment approach in order to minimize the risk of in-hospital contagious. For GBM patients, adjuvant treatments have been evaluated with even much more attention with regard to the expected efficacy. As a consequence, an hypofractioned radiotherapy regimen has been preferred in order to reduce the daily hospital accesses and, especially in pMGMT unmethylated patients, chemotherapy with Temozolomide was avoided. Here, we made a comprehensive evaluation of the neurooncological community suggestions regarding GBM treatment in the pre-vaccine era of COVID-19 pandemic.</p>}, number={3}, journal={Acta Biomedica Atenei Parmensis}, author={Internò, Valeria and Rudà, Roberta and Sergi, Maria Chiara and Soffietti, Riccardo and Porta, Camillo}, year={2022}, month={Jul.}, pages={e2022067} }