@article{Brili_Bei_Kounis_Chrysohoou_Antoniou_Kontopidou_Bonfanti_Cervellin_Tousoulis_Tsioufis_2021, title={Hypertensive crisis and pulmonary edema following rituximab-induced anaphylaxis }, volume={92}, url={https://mattioli1885journals.com/index.php/actabiomedica/article/view/11120}, DOI={10.23750/abm.v92iS1.11120}, abstractNote={<p>Rituximab is a monoclonal antibody against the protein CD20. Various lymphomas as well as non-malignant immune disorders are treated with this antibody. Hypersensitivity reactions associated with the use of rituximab include urticaria, hypotension, chest tightness, vomiting, oxygen desaturation and bronchospasm. A very uncommon case of hypertensive crisis and pulmonary edema following rituximab-induced hypersensitivity reaction in an 80-year-old man receiving rituximab for non-Hodgkin lymphoma is reported. Anaphylaxis manifesting as coronary vasospasm following drug treatment, including rituximab, could be proved a serious condition in patients who need specific treatment. In these patients desensitization protocols seem to be mandatory.</p>}, number={S1}, journal={Acta Biomedica Atenei Parmensis}, author={Brili, Stylian and Bei, Evangelia and Kounis, Nikolas G. and Chrysohoou, Christina and Antoniou, Christos-Konstantinos and Kontopidou, Flora and Bonfanti, Laura and Cervellin, Gianfranco and Tousoulis, Dimitrios Tousoulis and Tsioufis, Constantinos}, year={2021}, month={Oct.}, pages={e2021115} }