An unusual aggressive presentation of late onset sepsis due to Staphylococcus aureus MRSA producing Panton-Valentine Leukocidin in preterm neonate An unusual case of severe sepsis in preterm neonate
Main Article Content
Keywords
methicillin resistant Staphylococcus aureus,, neonate,, Panton-Valentine leukocidin,, late onset sepsis,, case report
Abstract
We report an unusual and rare case of infection from methicillin resistant Staphylococcus aureus (MRSA) producing Panton-Valentine leukocidin in a preterm neonate in NICU. On day of life 8, a preterm baby boy suddenly developed arthritis, giant cutaneous abscesses and an osteomyelitic focus with pour clinical condition. This very aggressive presentation of infection from MRSA push us to test Panton-Valentine leukocidin resulted positive and to test contacts to discover the bearer of the germ. MRSA producing Panton-Valentine leukocidin is an unusual case of infection in preterm neonate that has not been reported elsewhere. A very aggressive sepsis in neonates from Staphilococcus aureus should evoke the need to test Panton-Valentine leukocidin to rapidly establish an appropriate treatment. We underline also the importance to test contacts to establish promptly a decontaminant therapy
Downloads
References
2) Vanhecke C, Girerd R, Dujardin M, Zemali N, Manaquin R, Duport P, Traversier N, Mougin-Damour K, Vandroux D. Retrospective study of pneumonia due to Panton-Valentine leukocidin-producing Staphylococcus aureus in Reunion. Med Mal Infect. 2019 Oct;49(7):534-539
3) Leistner R, Kola A, Gastmeier P, Krüger R, Hoppe PA, Schneider-Burrus S, Zuschneid I, Wischnewski N, Bender J, Layer F, Niebank M, Scheibenbogen C, Hanitsch LG. Pyoderma outbreak among kindergarten families: Association with a Panton-Valentine leukocidin (PVL)-producing S. aureus strain. PLoS One. 2017 Dec 19;12(12):e0189961
4)Del Vecchio A, Ferrara T, Maglione M, Capasso L, Raimondi F. New perspectives in Respiratory Syncitial Virus infection. J Matern Fetal Neonatal Med. 2013 Oct;26 Suppl 2:55-9. doi: 10.3109/14767058.2013.831282
5)Khattak SG, Dady I, Mukherjee 1. Unusual presentation of late-onset disseminated staphylococcal sepsis in a preterm infant. BMJ Case Rep. 2019 Mar 15;12(3). pii: e226325. doi: 10.1136/bcr-2018-226325.
Article Sidebar
Article Details
How to Cite
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Transfer of Copyright and Permission to Reproduce Parts of Published Papers.
Authors retain the copyright for their published work. No formal permission will be required to reproduce parts (tables or illustrations) of published papers, provided the source is quoted appropriately and reproduction has no commercial intent. Reproductions with commercial intent will require written permission and payment of royalties.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.