YIELD, AND SAFETY OF ULTRASOUND GUIDED TRU CUT BIOPSY PERFORMED BY PULMONOLOGISTS TO DIAGNOSE THORACIC LESIONS
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Keywords
Benign, Biopsy, Malignant, Mediastinal, Pleural, Sudan, Thoracic, Tru-cut
Abstract
Introduction Thoracic lesions can result from malignant, benign, and inflammatory conditions, affecting the lung parenchyma, pleura, or mediastinum, and often require biopsy for definitive diagnosis. Objectives We aimed to assess the safety and diagnostic yield of ultrasound-guided tru-cut needle biopsy performed by pulmonologists for diagnosing thoracic lesions. Methods A prospective study was conducted among 45 patients undergoing ultrasound-guided tru-cut biopsies for diagnosing thoracic lesions. Data on patient demographics and procedure results were collected using a predesigned clinical data collection sheet. Results In this group of patients, ultrasound-guided biopsy performed by pulmonologists yielded adequate tissue samples and achieved an accurate diagnosis in 94.4% (42) of the cases. Malignant lesions were identified in 66.7% (30) of the patients, while 86.7% (39) experienced no complications. Additionally, no procedure-related mortalities were recorded. Conclusion Our results indicated that ultrasound-guided biopsy performed by pulmonologists has excellent diagnostic yielding results and safe technique for diagnosing thoracic lesions.
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[1] Khosla R, McLean AW, Smith JA. Ultrasound-guided versus computed tomography-scan guided biopsy of pleural-based lung lesions. Lung India [Internet]. 2016;33(5):487–92. Available from: http://dx.doi.org/10.4103/0970-2113.188961 [2] Rivera MP, Mehta AC, Wahidi MM. Establishing the diagnosis of lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest [Internet]. 2013;143(5 Suppl):e142S-e165S. Available from: http://dx.doi.org/10.1378/chest.12-2353 [3] Kim GR, Hur J, Lee SM, Lee H-J, Hong YJ, Nam JE, et al. CT fluoroscopy-guided lung biopsy versus conventional CT-guided lung biopsy: a prospective controlled study to assess radiation doses and diagnostic performance. Eur Radiol [Internet]. 2011;21(2):232–9. Available from: http://dx.doi.org/10.1007/s00330-010-1936-y [4] Chandrasekhar AJ, Reynes CJ, Churchill RJ. Ultrasonically guided percutaneous biopsy of peripheral pulmonary masses. Chest [Internet]. 1976;70(5):627–30. Available from: http://dx.doi.org/10.1378/chest.70.5.627 [5] Yang RJ, Yang YL, Ruan LT, Yuan LJ, Chao LJ, Chen S, et al. Clinical value of ultrasound-guided percutaneous biopsy of pulmonary lesions. Genet Mol Res [Internet]. 2015;14(2):3784–90. Available from: http://dx.doi.org/10.4238/2015.April.22.7 [6] Beslic S, Zukic F, Milisic S. Percutaneous transthoracic CT guided biopsies of lung lesions; fine needle aspiration biopsy versus core biopsy. Radiol Oncol [Internet]. 2012;46(1). Available from: http://dx.doi.org/10.2478/v10019-012-0004-4 [7] Chockalingam A, Hong K. Transthoracic needle aspiration: the past, present and future. J Thorac Dis [Internet]. 2015;7(Suppl 4):S292-9. Available from: http://dx.doi.org/10.3978/j.issn.2072-1439.2015.12.01 [8] Portable ultrasound devices in the Pre-Hospital Setting: A Review of Clinical and Cost-Effectiveness and Guidelines. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health. 2015 [9] Bhatnagar R, Corcoran JP, Maldonado F, Feller-Kopman D, Janssen J, Astoul P, et al. Advanced medical interventions in pleural disease. Eur Respir Rev [Internet]. 2016;25(140):199–213. Available from: http://dx.doi.org/10.1183/16000617.0020-2016 [10] Stigt JA, Groen HJM. Percutaneous ultrasonography as imaging modality and sampling guide for pulmonologists. Respiration [Internet]. 2014;87(6):441–51. Available from: http://dx.doi.org/10.1159/000362930 [11] Christiansen IS, Clementsen PF, Bodtger U, Naur TMH, Pietersen PI, Laursen CB. Transthoracic ultrasound-guided biopsy in the hands of chest physicians - a stepwise approach. Eur Clin Respir J [Internet]. 2019;6(1):1579632. Available from: http://dx.doi.org/10.1080/20018525.2019.1579632 [12] Reissig A, Copetti R. Lung ultrasound in community-acquired pneumonia and in interstitial lung diseases. Respiration [Internet]. 2014;87(3):179–89. Available from: http://dx.doi.org/10.1159/000357449 [13] Chen A, Hutchings J, Misselhorn D. Ultrasound-guided transthoracic forceps biopsy of a peripheral lung mass. J Bronchology Interv Pulmonol [Internet]. 2010;17(1):84–6. Available from: http://dx.doi.org/10.1097/LBR.0b013e3181ccae29 [14] El Ameen M, Gabir A, Mohammed M, Ahmed A, Ashkoub K, Bashir A. Role of ultrasound Guided biopsy of thoracic lesions. Sudan journal of medical sciences. 2013;8. [15] Hussain M, Ashraf M, Chima KK. Diagnostic Yield of Ultrasound-Guided Tru-Cut Biopsies of Peripheral Lesions by the Pulmonologist, Ann. Ann Pak Inst Med Sci. 2015;11(4):215–7. [16] El-Sharawy D, El-Shimy W, El-Emery F, El-Zaher A, El-Badry A. The diagnostic value of ultrasound-guided percutaneous transthoracic core-needle biopsy versus computed tomography-guided biopsy in peripheral intrathoracic lesions. Egypt J Bronchol. 2016;10(1):12. Available from: http://dx.doi.org/10.4103/1687-8426.176660 [17] Portela-Oliveira E, Souza CA, Gupta A, Bayanati H, Inacio J, Rakhra K. Ultrasound-guided percutaneous biopsy of thoracic lesions: high diagnostic yield and low complication rate. Clin Radiol [Internet]. 2021;76(4):281–6. Available from: http://dx.doi.org/10.1016/j.crad.2020.12.004 [18] Tikkakoski, T et al. “Thoracic lesions: diagnosis by ultrasound-guided biopsy.” RoFo: Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin vol. 159,5 (1993): 444-9. doi:10.1055/s-2008-1032795
