PLANT-MEDIATED SYNTHESIS OF AG-CU-ZN NANOPARTICLES USING ANTIGONON LEPTOPUS FLOWER EXTRACT AND ITS BIOEFFICACY
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Keywords
Green Synthesis, Antigonon leptopus, Ag-Cu-Zn, Characterization, Human Pathogens.
Abstract
Introduction: The scientific discipline of nanotechnology encompasses a wide range of topics, including surface science, organic chemistry, molecular biology, semiconductor physics, and microfabrication. Objective: The goal of the current work was to use Antgonon leptopus flower extract to swiftly synthesize Ag, Cu, and ZnNPs. The resulting nanoparticles were examined using a range of characterisation techniques, including as X-ray diffraction, UV-visible spectrum analysis, and scanning electron microscopy, and they were also examined in vitro against a few human pathogens. Results: Spectral analysis verified that the AgNPs' UV-visible absorption spectra had a distinctive peak at 260 nm. ZnNPs' absorption spectra, which were taken from the reaction media, showed an absorbance peak with the distinctive absorption peak seen at 320 nm, while CuNPs' absorption spectra showed a distinctive absorption peak that was noticed at 290 nm. Silver nanoparticles with an XRD pattern displayed 2𝜃 values of 7.6425, 20.1473, 23.2987, 27.4604, 31.8438, 33.4873, and 35.489. The XRD pattern of zinc nanoparticles was supported by the presence of peaks at 2𝜃 values of 9.5770, 14.4925, 16.4033, 19.0455, 21.4664, 23.7485, and 24.7928, respectively, and copper nanoparticles peaks at 2𝜃 values of 9.1995, 11.0902, 15.2634, 18.9091, 22.5422, 24.7211, and 27.9172. AgNPs are cube-shaped, as seen by the SEM analysis micrograph, and their average particle size was determined to be between 2 and 200 µm. Furthermore, substantial results were obtained from the biological activities of certain nanoparticles against antifungal (Candida albicans) and antibacterial (E. Coli, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylocouus aureus). Conclusion: Throughout the world, Antigonon leptopus is utilized in ethnomedicine to treat a wide range of conditions, including pain, diabetes, coughing, stomachaches, and dermatological issues. The current work demonstrates that the plant is the best resource for synthesizing AgNPs for future medicinal research. Keywords: Green Synthesis, Antigonon leptopus, Ag-Cu-Zn,Characterization, Human Pathogens.
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References
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