ANTIOXIDANT ACTIVITY AND RADICAL SCAVENGING EFFECT OF MUTINGIA CALABURA AND GLYCYRHIZZA GLABRA AND EVALUATION OF ITS CYTOTOXIC CAPACITY ON L929 (MURINE FIBROBLAST CELL LINE)
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Keywords
MTT assay, Antioxidant assay, L929 cell line, Mutingia calabura, and Glycyrhizza glabra.
Abstract
Mutingia calabura and Glycyrhizza glabra are widely cultivated for its valuable medicinal activity in the tropical region. The present study evaluated the antioxidant and cytotoxic effects of ethanolic plant extract of Mutingia calabura and Glycyrhizza glabra in combination. Antioxidant effects were assessed utilizing photometric assay in vitro, 2, 2-diphenylpicrylhydrazine as well as ferric, which reduces antioxidant strength, superoxide dismutase. The cytotoxicity assay was used to test cytotoxic activity for L929 (murine fibroblast cell line) cell lines. Our results show a plantation has promising anti-cancer action. The ethanolic plant extracts were able to extract compounds responsible for the antioxidant activity.
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