APPROACHES TO EFFICIENTLY ADDRESS THE INFLUENCE OF PRACTICE ON LONGITUDINAL INVESTIGATIONS OF COGNITIVE SENESCENCE
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Abstract
The incorporation of practice effects (PEs) into models of cognitive change has become considerably more intricate since the onset of the Covid-19 pandemic. This is because the incorporation of period and mode effects introduces bias into the estimation of cognitive trajectory. In order to assess the relationship between grasp strength and cognitive decline, as well as to forecast cognitive trajectories, we compared three prospective cohorts of Northern California Kaiser Permanente members. This was achieved through the implementation of the following three methodologies: 1) neglecting to recognise preliminary model (PE); 2) integrating a wave indicator; and 3) restricting PE to a subset of data preliminary model (APM) fit. Through the use of balanced, pre-pandemic data and the current age as the timescale, an APM-based correction for PEs reduced the discrepancy between within-person and between-person estimated age effects. The employed methodology failed to demonstrate any sensitivity in estimating the correlations between cognitive decline and grasping strength. Discussion: Implementing a preliminary model to restrict PEs is an adaptable and practical strategy that permits in-depth examination of cognitive transformation.
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